immature articular cartilage has stem cells (mature articular cartilage does not) Layers of Articular Cartilage: Normal articular cartilage is composed of three zones and the tidemark. zones based on the shape of the chondrocytes and the orientation of the type II collagen.4.2/5. Articular cartilage is the highly specialized connective tissue of diarthrodial joints. Its principal function is to provide a smooth, lubricated surface for articulation and to facilitate the transmission of loads with a low frictional coefficient (Figure 1). Articular cartilage is devoid of blood Cited by: 772.
What is an Articular Cartilage Defect and How is it Treated? by Steve A. Mora, MD. Orange County Knee Specialist. Please see our Knee Injury Protocol for additional information on this topic.. Three bones meet within the knee joint: the femur (thighbone), the tibia, (shin), and the patella (kneecap). Oct 05, 2001 · The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III, VI, IX, X, XI, XII and XIV all contribute to the mature matrix. In developing cartilage, the core fibrillar network is a cross-linked copolymer of collagens II, IX and XI.Cited by: 631.
As the first comprehensive comparison between juvenile and adult bovine articular cartilage at the tissue, cellular and molecular level's, our results strongly indicate that juvenile cartilage possesses greater regenerative capability and superior chondrogenic activity than adult cartilage.